How to Prevent Malaria When You Travel

Take antimalarial medication prescribed by a travel doctor 1-2 weeks before you leave, use it during your stay, and continue for 4 weeks after you return. Sleep under insecticide-treated nets and use DEET insect repellent on exposed skin every evening.

Budget
150-600 for full prevention (medication, repellent, net, clinic visit)
Duration
Preparation starts 4-6 weeks before departure
Best Time
Malaria transmission varies by region and season. Some areas have year-round risk; others spike during rainy seasons. Check with a travel doctor for your specific destination.
Visa Required
no

Step by step

  1. Schedule a travel medicine appointment 4-6 weeks before departure

    Call a travel clinic or your doctor and book an appointment. Bring your itinerary with specific cities and dates. This gives you time to get vaccines if needed and start antimalarial medication with proper timing.

  2. Get a malaria risk assessment for your destination

    Tell your doctor which regions you're visiting. Malaria risk varies dramatically — some areas have zero risk, others have year-round transmission. Your doctor will check current CDC or WHO guidelines for your exact locations and determine if medication is necessary.

  3. Receive your antimalarial prescription and instructions

    Your doctor will prescribe one of four options: atovaquone-proguanil (Malarone), doxycycline, mefloquine, or chloroquine/primaquine depending on drug resistance in your destination. Get clear written instructions on dosing and timing. Take this seriously — wrong timing reduces effectiveness.

  4. Start your medication on the correct schedule

    Begin antimalarials 1-2 weeks before arrival (atovaquone-proguanil and chloroquine) or 1-2 days before (doxycycline). This builds a protective level in your bloodstream before exposure. Set phone reminders if you take daily medication.

  5. Take medication consistently while traveling

    Take your pill at the same time each day with food (or as directed). Bring your full supply in original labeled bottles. Missing doses significantly reduces protection. If you vomit within 30 minutes of taking it, take another dose.

  6. Continue medication for 4 weeks after leaving the malaria zone

    Keep taking your antimalarial for the full 4 weeks after your last possible exposure. This kills parasites that may still be developing in your body. Set a calendar reminder so you don't stop early.

  7. Use DEET-based insect repellent every evening

    Apply 20-30% DEET to exposed skin (arms, legs, neck, behind ears) before dusk. Reapply after swimming or heavy sweating. Malaria mosquitoes bite mostly between dusk and dawn. Don't rely on repellent alone — it's backup to medication.

  8. Sleep under an insecticide-treated bed net

    Use a bed net treated with permethrin every night, even in cities. Hang it properly so mosquitoes can't access you. Tuck it under the mattress. If your accommodation doesn't have nets, buy a lightweight travel net before you leave ($15-30).

  9. Monitor for symptoms during and after travel

    Malaria symptoms (fever, chills, headache, muscle aches) can appear weeks to months after exposure. If you get sick, tell any doctor immediately that you've been in a malaria zone. Early diagnosis and treatment are critical.

Questions people ask

Do I really need antimalarial medication if I'm staying in a city?

It depends on the city and current transmission levels. Malaria exists in cities — urban areas in places like Lagos, Lagos, and parts of Southeast Asia have active transmission. Your doctor will assess your specific itinerary. Don't skip this step based on assumptions.

What if I forget to take a dose?

Take it as soon as you remember, unless it's almost time for your next dose. Don't double up. Missing one or two doses reduces protection but doesn't eliminate it if you take them consistently otherwise. This is why setting phone alarms helps.

Can I buy antimalarial medication at my destination instead of bringing it?

Don't count on it. Availability is inconsistent, quality is unreliable in some countries, and you need to start medication before exposure. Bring your full prescribed supply.

Do I need malaria prevention if I got malaria before?

Yes. Previous malaria doesn't give you immunity. You can get it again. Some antimalarials are different from what you took before, so tell your doctor about your previous infection.

What are the side effects of antimalarial medication?

Side effects vary by drug. Doxycycline can cause nausea and sun sensitivity. Mefloquine can cause neurological symptoms in some people. Atovaquone-proguanil is generally well-tolerated but expensive. Your doctor will discuss this and may test tolerance before your trip.

Is DEET safe to use repeatedly?

Yes. 20-30% DEET is safe for adults and children over 2 months old when used as directed. Wash it off before bed. Don't use it continuously 24/7, but nightly application during your trip is fine.

How do I know if I have malaria?

Symptoms include fever, chills, headache, muscle aches, and sometimes vomiting. They can appear 7 days to months after infection. If you get sick after traveling to a malaria zone, see a doctor immediately and tell them about your travel history. A blood test confirms malaria.

Total Estimate
150-600 total for prevention supplies
Bed Net If Needed
20-40
Travel Clinic Visit
100-300
Insect Repellent DEET
8-15
Antimalarial Medication
40-250 per month depending on drug type

Packing

  • Full supply of prescribed antimalarial medication
  • Lightweight insecticide-treated bed net
  • Long-sleeved shirt and pants for evening wear
  • Copy of your antimalarial prescription and doctor's contact info