Planning a Multi-Country Route in South America

Prioritize your route by geography to minimize long-haul flight costs and maximize time on the ground. Stick to one of the two main loops—the 'Gringo Trail' in the Andes or the Southern Cone circuit—to keep travel days under 12 hours.
- Budget
- 70 dollars per day estimate
- Duration
- 21 days recommended
- Best Time
- September to November or March to May
- Visa Required
- Depends; check individual country consulate pages for your specific nationality.
Step by step
Select one primary geographical corridor
Do not attempt to see the entire continent in one trip. Choose either the Northern Andean route (Colombia, Ecuador, Peru) or the Southern Cone (Argentina, Chile, Uruguay, Brazil). North-to-south or south-to-north is easier than criss-crossing.
Choose your primary transport method
If you have more time than money, use long-distance buses (e.g., Cruz del Sur or Pullman). If you have less than 4 weeks, budget for domestic flights (LATAM or Sky Airline) to avoid 20+ hour bus rides over mountain passes.
Account for altitude and climate
Start at sea level and work your way up to the high Andes (Cusco, La Paz) over 7-10 days to avoid severe altitude sickness. If traveling in June–August, focus on the North; if November–March, head South.
Book international hubs only
Book your arrival flight into a major hub like Lima (LIM), Santiago (SCL), or Bogotá (BOG). Do not book internal multi-city tickets months in advance, as your timeline will inevitably change once you start traveling.
Questions people ask
Is it better to fly or take the bus?
Take the bus for distances under 500km to see the landscape; fly for anything longer to avoid exhausting multi-day travel marathons.
Do I need to speak Spanish?
You can navigate the main tourist trail with English, but knowing basic Spanish numbers and phrases for bus stations and markets is mandatory for avoiding 'tourist pricing'.
- Notes
- Budget 60 USD/day for backpacking/buses and 100+ USD/day if taking internal flights and private tours.
- Daily Spend
- 60-80 dollars per person
Packing
- Merino wool layers (essential for Andean temperature shifts)
- Unlocked smartphone for local SIM cards
- Universal power adapter with surge protection
- High-quality water filtration bottle (like Grayl) for remote areas
Itinerary
- 1-10 — Plan your next bus or short-haul flight segment. — Fly into Bogotá or Lima. — Focus on city exploration and acclimatization. — Expect daily temperatures to fluctuate significantly if in the mountains.
- 11-20 — Evaluate pace; if exhausted, add one extra night in current location. — Transit to secondary regions or smaller towns. — Engage in local transit or hiking. — Check bus schedules 48 hours in advance.